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Rho GDP-dissociation inhibitor 3

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Protein Overview: Rho GDP-dissociation inhibitor 3

Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.

Synonyms: Rho GDI 3, Rho-GDI gamma, Rho-GDI2

Gene name: Arhgdig

Database References

UniProtID GeneID
Mus musculus Q62160 14570
Homo sapiens Q4TT69 398
Bos taurus Q0II80 613745

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017