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Rho guanine nucleotide exchange factor 12

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Protein Overview: Rho guanine nucleotide exchange factor 12

May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.

Synonyms: Leukemia-associated RhoGEF

Gene name: ARHGEF12

Database References

UniProtID GeneID
Homo sapiens O15086 23365
Mus musculus E9QPW9

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017