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Polyclonal Rabbit anti-CASP3 antibody Abcam #ab13847

Polyclonal Rabbit anti-CASP3 antibody

  • Company: Abcam
  • Product code: ab13847
  • Review rating:3.00 (1 review)
  • Verified publications: 16

Product Details

1DB_ID: 1DB-001-0000107165
Company: Abcam
Company product code: ab13847
Product name: Anti-active Caspase 3 antibody
Product type: Primary, Antibody
Size/Price: 100 µg/
Target: CASP3
Tested applications: FACS, ICC, IF, WB
Host: Rabbit
Reacts with: Human, Mouse, Rat, Pig, Xenopus, Zebrafish, Drosophila, Deer, Rhesus Macaque
Clonality: Polyclonal
Description: Rabbit polyclonal to active Caspase 3
Immunogen: Synthetic peptide conjugated to KLH derived from within residues 150 - 250 of Human active Caspase 3.
Specificity: Ab13847 detects the large (17 kDa) subunit from recombinant active Caspase 3. Ab13847 also detects the 17 kDa subunit in HeLa, A431 and Jurkat lysates.
Storage Buffer: Preservative: 0.02% Sodium Azide Constituents: 1% BSA, PBS, pH 7.4
Purity: Affinity purified
Isotype: IgG
Concentration: 100 µg at 1mg/ml
Storage instructions: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Alternative Names: APOPAIN antibody;Apopain precursor antibody;Apopain precursor antibody
Relevance: The caspase family of cysteine proteases play a key role in apoptosis. Caspase 3 is the most extensively studied apoptotic protein among caspase family members. Caspase 3 is synthesized as inactive pro enzyme that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by other upstream proteases (e.g. Caspases 8, 9 and 10). The processed form of Caspase 3 consists of large (17kDa) and small (12kDa) subunits which associate to form an active enzyme. Caspase 3 is cleaved at

Reviews (1)

3 - Good (Publishable / Would use again)
Application: IHC
Sample: Pig Tissue sections (heart)
Buffer: Serum: Concentration 10% - Temperature 25°C
Dilution: 1/100
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Verified publications (16)

BMC Dev. Biol., 2010
Female reproductive potential, or the ability to propagate life, is limited in mammals with the majority of oocytes lost before birth. In mice, ...
Development, 2010
In mammals, the loss of a limb is irreversible. By contrast, urodele amphibians and teleost fish are capable of nearly perfect regeneration of lost ...
Tissue Eng Part A, 2009
When incubated under simulated microgravity (s-microg), endothelial cells (EC) form tubular structures that resemble vascular intimas. This delayed ...
Am. J. Respir. Crit. Care Med., 2009
Bronchopulmonary dysplasia (BPD) and emphysema are characterized by arrested alveolar development or loss of alveoli; both are significant global ...
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