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Polyclonal anti-CCL2 antibody Boster Immunoleader #PA1356

Polyclonal anti-CCL2 antibody

Product Details

1DB_ID: 1DB-001-0001404633
Company: Boster Immunoleader
Company product code: PA1356
Product name: Polyclonal Anti-MCP-1
Product type: Primary, Antibody
Size/Price: 100µg/vial/
Target: CCL2
Tested applications: WB
Reacts with: Human, Mouse, Rat
Clonality: Polyclonal
Description: Immunity Purified Rabbit Polyclonal Anti Chemokine (C-C motif) Ligand 2 (CCL2) Antibody IgG
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human MCP-1, different from the mouse and rat sequence by two amino acids
Purity: Affinity purified
Isotype: IgG
Storage instructions: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Background: Monocyte chemoattractant protein-1 (MCP-1), a member of the chemokine (chemotactic cytokine) family, is a potent monocyte agonist that is upregulated by oxidized lipids.1 MCP-1 is also known as CCL2, SCYA2, MCAF. MCAF is a member of family of factors involved in immune and inflammatory responses. The amino acid sequence deduced from the nucleotide sequence reveals the primary structure of the MCAF precursor to be composed of a putative signal peptide sequence of 23 amino acid residues and a mature MCAF sequence of 76 amino acid residues.2 MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder.3 Human MCP-1 is a 8.7KDa non-glycoprotein, consisting of 99 amino acids in precursor form and 76 amino acids in mature form.
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500µg/ml.
Gene Name: CCL2
Protein Name: C-C motif chemokine 2
Gene Full Name: chemokine (C-C motif) ligand 2
Synonyms: MCP-1; SMC-CF; SCYA2; MCAF; GDCF-2; HC11; MCAF; MCP1; MGC9434; HC11; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte secretory protein JE; Small-inducible cytokine A2
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN68.
Uniprot ID: P13500

Quality control data

Lane 1: Rat Brain Tissue LysateLane 2: Rat Brain Tissue LysateLane 3: Rat Liver Tissue LysateLane 4: Rat Pancreas Tissue LysateLane 5: MCF-7 Cell Lysate Lane 6: Hela Cell LysateLane 7: MM453 Cell LysateLane 8: MM231 Cell LysateLane 9: HT1080 Cell LysateLane 10: MK(55KD)
Click image to view full-size

Lane 1: Rat Brain Tissue Lysate
Lane 2: Rat Brain Tissue Lysate
Lane 3: Rat Liver Tissue Lysate
Lane 4: Rat Pancreas Tissue Lysate
Lane 5: MCF-7 Cell Lysate Lane 6: Hela Cell Lysate
Lane 7: MM453 Cell Lysate
Lane 8: MM231 Cell Lysate
Lane 9: HT1080 Cell Lysate
Lane 10: MK(55KD)

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About Boster Immunoleader

Boster Biological Technology, Ltd. has consistently focused on the manufacture, research, sale and distribution of immunological reagents. With innovative solutions and high quality, their products enjoy the high reputation and customer loyalty in immunological and molecular biological fields. As a leading supplier, Boster can provide the best products and service to meet customers' needs. Boster was founded in 1993 and manufactures thousands of antibodies, hundreds of Elisa kits and a series of detection kits in immunological and molecular fields. They also have established a strict quality control systerm to ensure that their products can mostly serve customers' research. Meanwhile, their R&D system has continously helped them to generate new produts. Boster tries its best to seek antibodies with much higher quality, which have been proved by their polyclonal antibodies. Boster's goal is to continue to earn customers' trust as a quality supplier.