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Monoclonal Rat anti-KIT antibody eBioScience #47-1172

Monoclonal Rat anti-KIT antibody

  • Company: eBioScience
  • Product code: 47-1172
  • Review rating:3.50 (2 reviews)

Product Details

1DB_ID: 1DB-001-0000263819
Company: eBioScience
Company product code: 47-1172
Product name: Anti-Mouse CD117 (c-Kit) APC-eFluor® 780
Product type: Primary, Antibody
Multiple sizes available: 100 ug / ; 25 ug /
Target: KIT
clone: ACK2
Tested applications: FACS
Host: Rat
Reacts with: Mouse
Clonality: Monoclonal
Conjugation: APC, eFluor® 780
Isotype: IgG2B
Product Description: The ACK2 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145 kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells. ACK2 has been reported to be a blocking antibody.

Reviews (2)

3 - Good (Publishable / Would use again)
Application: FACS
Sample: Developing Lymphocyte
Buffer: HBSS
Dilution: 1/200
4 - Excellent (Publishable / Ideal reagent)
Application: FACS
Sample: Ex Vivo-Derived DN1 Thymocyte Subsets
Buffer: HBSS-BSA(2.5%)
Dilution: 1:300
See all reviews

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