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Polyclonal Rabbit anti-CASP9 antibody EMD Millipore #AB3629

Product Details

1DB_ID: 1DB-001-0000846490
Company: EMD Millipore
Company product code: AB3629
Product name: Anti-Caspase 9, active (cleaved) form
Product type: Primary, Antibody
Size/Price: 50 µg/
Target: CASP9
Tested applications: ICC, IP, WB
Host: Rabbit
Reacts with: Human
Clonality: Polyclonal
Modification: Cleaved
Immunogen: Synthetic peptide. FQEGLRTFDQLD
Specificity: AB3629 detects only the cleaved large 37kDa subunit and does not detect the precursor form in cells undergoing apoptosis. It also does not detect other caspases.
Storage instructions: Maintain frozen at -20°C. For optimal storage, aliquot and freeze at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Background: Caspase-9 is an important member of the caspase family. When cytochrome c is released from the mitochondria early upon apoptosis induction, it associates with Apaf-1 and procaspase-9 and forms an apoptosome. This complex cleaves procaspase-9 into a large 37kDa subunit and a small 10kDa subunit.
Subcategory: Apoptosis & Cancer
Gene ID: NM_001229.2, NM_032996.1

Quality control data

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Verified publications (1)

J. Cell. Physiol., 2004
Geldanamycin (GA) binds to heat shock protein 90 (Hsp90) and interferes with its function which is to protect various cellular proteins involved in ...
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About EMD Millipore

EMD Millipore Bioscience delivers new technologies & workflow solutions that enable researchers to understand complex biological systems & identify new targets.